endo-avoid-sympathomimetic-cvd
A clinical support tool for identifying safe, non-sympathomimetic pharmacological weight-loss options for high-risk cardiac patients.
Install
mkdir -p .claude/skills/endo-avoid-sympathomimetic-cvd && curl -L -o skill.zip "https://agentskills.codes/api/skills/download/16927" && unzip -o skill.zip -d .claude/skills/endo-avoid-sympathomimetic-cvd && rm skill.zipInstalls to .claude/skills/endo-avoid-sympathomimetic-cvd
Activation
This is the description your AI agent reads to decide when to run this skill — the better it matches your request, the more reliably it fires.
Recommends using non‑sympathomimetic agents (lorcaserin, orlistat) for pharmacological weight loss in patients with cardiovascular disease. Triggers include clinician questions such as “What weight‑loss medication is safest for this patient with coronary artery disease?” or “Should I avoid phentermine in a patient with prior stroke seeking obesity treatment?”.Key capabilities
- →Gather patient information on cardiovascular disease (CVD) presence
- →Assess BMI and review current medications for sympathomimetic contraindications
- →Determine if the patient is seeking pharmacological weight loss with CVD
- →Choose lorcaserin if no concomitant serotonergic drugs or psychiatric contraindications
- →Select orlistat if no chronic malabsorption, cholestasis, pregnancy, or breastfeeding
- →Prescribe lorcaserin or orlistat as an adjunct to lifestyle modification
How it works
The skill gathers patient information to determine CVD presence and other contraindications. It then rules in/out the need for specific non-sympathomimetic agents and classifies the appropriate medication (lorcaserin or orlistat) based on patient conditions.
Inputs & outputs
When to use endo-avoid-sympathomimetic-cvd
- →Choose weight-loss meds for CAD patients
- →Assess sympathomimetic contraindications
- →Document cardiac safety for prescriptions
About this skill
Avoid sympathomimetics in CVD for weight loss
STEP 1 — Gather Information
Determine presence of cardiovascular disease (CAD, prior stroke, heart failure, PAD) or uncontrolled hypertension/history of heart disease; assess BMI ≥27 kg/m² with comorbidity or ≥30 kg/m²; review current medications for sympathomimetic contraindications (MAOIs, SSRIs) and obtain baseline weight, BP, heart rate.
STEP 2 — Rule In / Rule Out
If patient has CVD (or uncontrolled hypertension/history of heart disease) and is seeking pharmacological weight loss → proceed; otherwise, standard weight‑loss medication selection applies.
STEP 3 — Classify or Stratify
Choose lorcaserin if no concomitant serotonergic drugs (SSRI/SNRI/MAOI/triptan) and no psychiatric contraindications; otherwise select orlistat if no chronic malabsorption, cholestasis, pregnancy, or breastfeeding.
STEP 4 — Decide
Prescribe lorcaserin 10 mg BID or orlistat 120 mg TID as adjunct to lifestyle modification; document avoidance of phentermine/diethylpropion and arrange monthly follow‑up for efficacy and safety.
Clinical Guardrails / Mimics / Pitfalls
Do not prescribe sympathomimetics (phentermine, diethylpropion) in CVD; avoid lorcaserin with serotonergic agents due to serotonin syndrome risk; avoid orlistat in patients with chronic malabsorption, cholestasis, pregnancy, or breastfeeding; monitor BP and heart rate; ensure concurrent diet, exercise, and behavioral therapy.
Concrete Clinical Example
A 60‑year‑old woman with prior ischemic stroke (BMI 31) asks for weight‑loss aid; she takes atorvastatin and aspirin, no antidepressants. After confirming CVD and no serotonergic meds, orlistat 120 mg TID is started; phentermine is avoided due to stroke history.
Source: Pharmacological Management of Obesity: An Endocrine Society Clinical Practice Guideline, Endocrine Society, 2015, DOI:10.1210/jc.2014-3415
When not to use it
- →When the patient does not have CVD or uncontrolled hypertension/history of heart disease
- →When the patient is not seeking pharmacological weight loss
Limitations
- →The skill recommends using non-sympathomimetic agents.
- →The skill avoids lorcaserin with serotonergic agents due to serotonin syndrome risk.
- →The skill avoids orlistat in patients with chronic malabsorption, cholestasis, pregnancy, or breastfeeding.
How it compares
This skill provides a structured, step-by-step clinical guideline for selecting weight-loss medication for patients with cardiovascular disease, specifically avoiding sympathomimetics, unlike a general medication recommendation system.
Compared to similar skills
endo-avoid-sympathomimetic-cvd side by side with the closest alternatives in the catalog.
| Skill | Installs | Updated | Safety | Difficulty |
|---|---|---|---|---|
| endo-avoid-sympathomimetic-cvd (this skill) | 0 | 1mo | No flags | Advanced |
| legal-risk-assessment | 3 | 6mo | No flags | Intermediate |
| lex | 0 | 4mo | Review | Advanced |
| neqsim_standard_requirement_extraction | 0 | 1mo | No flags | Intermediate |
Try saying
Example prompts that trigger this skill in your AI assistant.
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